New JLA vs. Old Crime Syndicate
I'm looking forward to seeing the currently motley Justice League go up against the Crime Syndicate. As others have said, we've seen the Big Seven JLA go up against them many times. But this will be the first time that a replacement League has faced off against them (as far as I know).
It should make for some interesting match-ups. Chief amongst them would be Jesse Quick vs. Johnny Quick. After all, the characters have nothing in common, but happen to share a name. That should bring about some delightful conflict, if nothing else.
I do notice that the caucasian Power Ring has returned and it makes me wonder... Is the membership of the Crime Syndicate still affected by the membership of the main Earth Justice League? That's the sort of thing I'd imagine James Robinson pulling out and using in a story...